FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mei-218unspecified
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General Information
Symbol
Dmel\mei-218unspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0051352
Feature type
allele
Associated gene
Dmel\mei-218
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Meiotic crossing-over is reduced by a factor of 1/12 in homozygous females. The frequency of gene conversion at the ry locus is unaffected in homozygous females.

        (Carpenter, 1982)

        Mutants are recombination defective. Mutants do not show sensitivity to methyl methanesulfonate, nitrogen mustard, UV light, γ rays or X rays. Mutants are not defective in repair of single strand breaks, excision repair or post-replication repair. Homozygotes and hemizygotes do not show an increased frequency of spontaneous chromosome aberrations in neuroblast metaphases compared to wild-type larvae.

        (Gatti, 1979)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        mei-218unspecified is rescued by mei-218+t15

        (Liu et al., 2000)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        mei-218unspecified
        unspecified
        (Carpenter, 1982)
        Name Synonyms
        Secondary FlyBase IDs
          References (5)