FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bowl4
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General Information
Symbol
Dmel\bowl4
Species
D. melanogaster
Name
FlyBase ID
FBal0051734
Feature type
allele
Associated gene
Dmel\bowl
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Wang and Coulter, 1996)
Progenitor genotype
Cytology
Description

Amino acid replacement: D279N.

(Wang and Coulter, 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:3,780,560..3,780,560 [+]
Nucleotide change:

G3780560A

Reported nucleotide change:

G1179A

Amino acid change:

D279N | bowl-PA; D279N | bowl-PB; D279N | bowl-PC; D279N | bowl-PD; D279N | bowl-PF; D279N | bowl-PG; D279N | bowl-PH

Reported amino acid change:

D279N

Comment:

2nd zinc finger, residue 15

(Wang and Coulter, 1996)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethality occurs during embryonic, larval and pupal stages. The flies that die as embryos exhibit the 'tail-up' phenotype and defects in the mandible and maxilla. Hindgut is drastically reduced, proventriculus is absent. Moderate bowl allele.

      (Wang and Coulter, 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      bowl4
      Name Synonyms
      Secondary FlyBase IDs
        References (1)