FB2026_02 , released June 18, 2026
Allele: Btau\SODAct5C.PRa
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General Information
Symbol
Btau\SODAct5C.PRa
Species
B. taurus
Name
Actin 5C promoter construct a of Reveillaud
FlyBase ID
FBal0055334
Feature type
allele
Associated gene
Btau\SOD
Associated Insertion(s)
Carried in Construct
P{bSOD}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Reveillaud et al., 1994, Fleming et al., 1992, Reveillaud et al., 1991)
Progenitor genotype
Carried in construct
P{bSOD}
Cytology
Description

Expression of an 0.886kb EcoRI fragment of Btau\SOD cDNA, coding region and 87bp of 5' untranslated sequence including the 5bp Kozak consensus sequence, is driven by an EcoRI-SalI Act5C promoter.

(Reveillaud et al., 1991)
Allele components
Component
Use(s)
Regulatory region(s)
Act5C
Encoded product / tool
Btau\SOD
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of P{bSOD} confers resistance to paraquat and a slight but significant increase in the mean lifespan of transgenic flies.

      (Reveillaud et al., 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of P{bSOD} restores Sodn1 male fertility and resistance to paraquat to apparently normal levels. Adult life is restored to only 30% of normal and resistance to hyperoxia is 90% of that found in control flies.

      (Reveillaud et al., 1994)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Btau\SODAct5C.PRa
      Name Synonyms
      Actin 5C promoter construct a of Reveillaud
      (Reveillaud et al., 1991)
      Secondary FlyBase IDs
        References (3)