FB2026_02 , released June 18, 2026
Allele: Ecol\lacZrun.-6GBrb
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General Information
Symbol
Ecol\lacZrun.-6GBrb
Species
E. coli
Name
FlyBase ID
FBal0055668
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{run-lacZ.-6GBrb}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Wolff et al., 1999, Klingler et al., 1996)
Progenitor genotype
Ecol\lacZrun.-6G
(Wolff et al., 1999)
Carried in construct
P{run-lacZ.-6GBrb}
Cytology
Description

Deletion of -5kb to immediately upstream of the start of transcription, within the run upstream region.

(Wolff et al., 1999)

BglII-BamHI run enhancer fragment and 1.3kb run promoter fragment of immediate upstream DNA (-1300 to +450bp) drives lacZ expression.

(Klingler et al., 1996)
Allele components
Component
Use(s)
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      This larger basal promoter alone confers transcriptional activation at a low level in all cells of the blastoderm embryo, activation above this level as well as inhibition could be detected.

      (Klingler et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZrun.-6GBrb
      lacZrun.-6GBrb
      Name Synonyms
      Secondary FlyBase IDs
        References (2)