FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\wX96.hs
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General Information
Symbol
Dmel\wX96.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0055934
Feature type
allele
Associated gene
Dmel\w
Associated Insertion(s)
Carried in Construct
P{FRT(X96)}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Ahmad and Golic, 1996)
Progenitor genotype
w+mW.hs
(Ahmad and Golic, 1996)
w+mW.FRT.hs
(Ahmad and Golic, 1996)
Carried in construct
P{FRT(X96)}
Cytology
Description

Direct FRT sequences flank the 3' portion of w+mW.hs (the five 3' exons followed by the stop codon) and the 5' portion of w+mW.Scer\FRT.hs (promoter and followed by the first exon).

(Ahmad and Golic, 1996)
Allele components
Component
Use(s)
Encoded product / tool
w
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      P{hsFLP} P{FRT(X96)} individuals heat shocked during mid-third instar larvae show pigment only in the posterior of the eye, the mitotic program is essentially finished. The anterior remains unpigmented because the excised extrachromosomal gene is lost when cells divide. Heat shock during early pupae (by which time cell division is completed) causes almost entirely pigmented eyes. Heat shock at late pupae show fairly uniform but light pigmentation as the eyes competence to make pigment decreases at this later stage.

      (Ahmad and Golic, 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The w gene is turned off in the P{FRT(X96)} construct and Scer\FLP1-mediated expression produces a functional extrachromosomal w gene that can be expressed in non-dividing cells (extrachromosomal portion is lost in dividing cells).

      (Ahmad and Golic, 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      wX96.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (3)