FlyBase Allele Report: Dmel\vvl[unspecified]

General Information

Symbol

Dmel\vvl^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0055940

Feature type

allele

Associated gene

Dmel\vvl

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy

(Inbal et al., 2003)

visible (with In(3LR)282)

(Inbal et al., 2003)

Phenotype Manifest In

abdominal lateral pentascolopidial chordotonal organ lch5

(Inbal et al., 2003)

desC neuron

(Inbal et al., 2003)

desD neuron

(Inbal et al., 2003)

larval tracheal system

(Sotillos et al., 2010)

wing vein L4 (with In(3LR)282)

(Inbal et al., 2003)

Detailed Description

Statement

Reference

In vvl^unspecified an aberrant tracheal tree is formed that does not fuse in a longitudinal dorsal trunk.

(Sotillos et al., 2010)

vvl^unspecified/In(3LR)282 adults lack wing vein L4. Mutants have misplaced lch5 organs. The neurons of the desC and desD organs are missing in 53-69% of segments. Sheath cells are missing in 24% of desD and 57% of desC organs. The two outer support cells are both missing in 18% of desD and 61% of desC organs, and only rarely there is only one cell present.

(Inbal et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

vvl^unspecified has phenotype, enhanceable by Egfr^t1/Egfr^f11

(Diaz-Benjumea and Garcia-Bellido, 1990)

NOT suppressed by

Statement

Reference

vvl^unspecified has larval tracheal system phenotype, non-suppressible by Ecol\lacZ^vvl.345

(Sotillos et al., 2010)

vvl^unspecified has larval tracheal system phenotype, non-suppressible by Ecol\lacZ^vvl.1+2

(Sotillos et al., 2010)

Enhancer of

Statement

Reference

vvl^unspecified/vvl[+] is an enhancer of phenotype of Egfr^t1/Egfr^f11

(Diaz-Benjumea and Garcia-Bellido, 1990)

Additional Comments

Genetic Interactions

Statement

Reference

Egfr^t1/Egfr^f11 vvl^unspecified/+ double mutants have a superadditive phenotype.

(Diaz-Benjumea and Garcia-Bellido, 1990)

Xenogenetic Interactions

Statement

Reference

Expression of Ecol\lacZ^vvl.345 is unable to rescue the tracheal network defects seen in vvl^unspecified mutant embryos.

Expression of Ecol\lacZ^vvl.1+2 is unable to rescue the tracheal network defects seen in vvl^unspecified mutants.

(Sotillos et al., 2010)

Complementation and Rescue Data

Partially rescued by

vvl^unspecified is partially rescued by vvl^UAS.cBa/Scer\GAL4^arm.PS

(Inbal et al., 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

unspecified

(Diaz-Benjumea and Garcia-Bellido, 1990)

vvl^unspecified

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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