FlyBase Allele Report: Dmel\run[VP16.1-506.hs]

General Information

Symbol

Dmel\run^{VP16.1-506.hs}

Species

D. melanogaster

Name

FlyBase ID

FBal0056218

Feature type

allele

Associated gene

Dmel\run

Associated Insertion(s)

Carried in Construct

P{Run^Act-VP16}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Jimenez et al., 1996)

Progenitor genotype

Carried in construct

P{Run^Act-VP16}

Cytology

Description

A heat inducible Hsp70 promoter drives expression of run coding amino acid residues 1-506 (lacks the three C-terminal amino acids RPY) fused to the VP16 transcriptional activation domain.

(Jimenez et al., 1996)

Allele components

Component

Use(s)

Regulatory region(s)

Hsp70

Encoded product / tool

run

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

pair rule phenotype

(Jimenez et al., 1996)

Phenotype Manifest In

Detailed Description

Statement

Reference

Heat induced expression in 140-170 min blastoderm embryos causes a ftz-like pair-rule phenotype or stronger segmentation defects in which further abdominal segments are fused.

(Jimenez et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

run::VP16^1-506.hs

run^{1-506.hs.T:Hsim\VP16}

run^{VP16.1-506.hs}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close