FB2026_03 , released September 17, 2026
Allele: Dmel\ro252
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General Information
Symbol
Dmel\ro252
Species
D. melanogaster
Name
FlyBase ID
FBal0056248
Feature type
allele
Associated gene
Dmel\ro
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Heberlein et al., 1994)
Progenitor genotype
Cytology
Description

Stop codon created two amino acids C-terminal to the homeodomain.

(Heberlein et al., 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:26,877,561..26,877,561 [-]
Nucleotide change:

C26877561T

Amino acid change:

Q253term | ro-PA; Q253term | ro-PB

Reported amino acid change:

?253term

Comment:

Reported as a stop codon two amino acids C-terminal to the homeodomain. A 252 amino acid translation product is produced.Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Heberlein et al., 1994)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Rough eye phenotype, 18% ommatidia are wild type.

      (Heberlein et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Weak ro allele.

      (Heberlein et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ro252
      Name Synonyms
      Secondary FlyBase IDs
        References (1)