FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.
Whereas in wild type ovarian follicles the Golgi apparatus and yolk spheres are preferentially labelled by osmium zinc iodide, in mutant follicles the Golgi apparatus and nearby vesicles showed dramatically reduced staining.
Follicles develop normally until vitellogenesis, when they begin to degenerate. The follicle cell-oocyte interface of a stage 7 ovarian chamber lacks the typical interdigitating microvilli and has only small clusters of intramembrane particles. The macular plaques of the nurse cell-oocyte interface of stage 4 to 6 ovarian follicles are more heterogeneously shaped than in wild-type females.
Transplantation experiments show that fs(2)A17unspecified ovaries develop autonomously in wild-type hosts and that fs(2)A17unspecified hosts support vitellogenesis in implanted normal and ap1 ovaries.
