FB2026_03 , released September 17, 2026
Allele: Dmel\kna.hs
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General Information
Symbol
Dmel\kna.hs
Species
D. melanogaster
Name
antisense heat shock construct
FlyBase ID
FBal0057685
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

Antisense kn RNA is expressed using an Hsp70 promoter.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos carrying kna.hs show no defects if heat shocked at 37oC for 1 hour between 4 and 6 hours of development. Most embryos carrying kna.hs fail to hatch if heat shocked at 37oC for 1 hour between 3 and 4 hours of development. Approximately 80% of these embryos develop to the point of making cuticle and consistently show head defects, with a drastic reduction or absence of the lateral graten.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
cola.hs
kna.hs
Name Synonyms
antisense heat shock construct
Secondary FlyBase IDs
    References (1)