FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rh5ninaE.PC
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General Information
Symbol
Dmel\Rh5ninaE.PC
Species
D. melanogaster
Name
neither inactivation nor afterpotential E promoter construct of Chou
FlyBase ID
FBal0058344
Feature type
allele
Associated gene
Dmel\Rh5
Associated Insertion(s)
Carried in Construct
P{Rh1+5}
Key Links
Transgenic product class
cDNA
(Chou et al., 1996)
wild_type
(Chou et al., 1996)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Chou et al., 1996)
wild_type
(Chou et al., 1996)
Mutagen
in vitro construct
(Chou et al., 1996)
Progenitor genotype
Carried in construct
P{Rh1+5}
Cytology
Description

KpnI-SpeI fragment of ninaE containing 2.4kb of promoter sequence and 33bp of 5' untranslated region drives expression of 1.3kb EcoRI fragment of Rh5 11 cDNA.

(Chou et al., 1996)
Allele components
Component
Use(s)
Regulatory region(s)
ninaE
ninaE_(Rh1+5)
Encoded product / tool
Rh5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Rh5ninaE.PC is a suppressor of abnormal thermotaxis | larval stage phenotype of ninaE17

      (Shen et al., 2011)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Rh5ninaE.PC is a suppressor of phenotype of ninaE17

      (Salcedo et al., 1999, Chou et al., 1996)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Rh5ninaE.PC rescues the ability of ninaE17 larvae to strongly discriminate between 18[o]C and 24[o]C in a binary choice thermotaxis assay.

      (Shen et al., 2011)

      The electroretinograms of homozygous ninaE17 flies have no on- or off-transients and the magnitude of depolarisation is dramatically reduced compared to wild-type. The light response in the ERG is completely restored if the flies are carrying Rh5ninaE.PC.

      (Salcedo et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Rh5ninaE.PC
      Name Synonyms
      neither inactivation nor afterpotential E promoter construct of Chou
      (Chou et al., 1996)
      Secondary FlyBase IDs
        References (5)