FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Nrx-IV1817
Open Close
General Information
Symbol
Dmel\Nrx-IV1817
Species
D. melanogaster
Name
FlyBase ID
FBal0058472
Feature type
allele
Associated gene
Dmel\Nrx-IV
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Banerjee et al., 2011)
Mutagen
ethyl methanesulfonate
(Baumgartner et al., 1996)
Progenitor genotype
Cytology
Description

Deletion of 16 nucleotides including nucleotides 3797-3801 of an exon, as well as 11 nucleotides from the next intron. This results in a frame shift which adds an additional 9 unrelated amino acids before a stop codon.

(Banerjee et al., 2011)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:12,155,786..12,155,801 [+]
Comment:

Deletion of 16 nucleotides including nucleotides 3797-3801 (relative to cDNA GB:X86685) from an exon, as well as 11 nucleotides from the adjacent intron. This results in a frame shift which adds an additional 9 unrelated amino acids before a stop codon.

(Banerjee et al., 2011)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant embryos show complete loss of septate junctions between epithelial cells, but have normal adherens junctions.

      (Banerjee et al., 2011)

      Transheterozygotes with Df(3L)vin8 or Df(3L)BK9 are lethal, rare adults escapers are occasionally obtained.

      (Baumgartner et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Nrx-IV1817
      Nrx1817
      (Baumgartner et al., 1996)
      nrx IV1817
      (Banerjee et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)