FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\RasGAP1EP45
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General Information
Symbol
Dmel\RasGAP1EP45
Species
D. melanogaster
Name
FlyBase ID
FBal0058737
Feature type
allele
Associated gene
Dmel\RasGAP1
Associated Insertion(s)
P{EP}RasGAP1EP45
Carried in Construct
Key Links
Allele class

wild-type allele

Mutagen
Nature of the Allele
Allele class

wild-type allele

(Rorth, 1996)
Mutagen
P-element activity
(Rorth, 1996)
Progenitor genotype
Associated Insertion(s)
P{EP}RasGAP1EP45
Cytology
Description

Insertion of a P{EP} element approximately 20bp upstream of the Gap1 transcription start site.

(Rorth, 1996)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies have rough eyes when Gap1EP45 expression is driven by Scer\GAL4hs.2sev.

      (Rorth, 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      RasGAP1EP45, Scer\GAL4hs.2sev has visible phenotype, enhanceable by Ras85D05703

      (Rorth, 1996)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      RasGAP1EP45, Scer\GAL4hs.2sev has eye phenotype, enhanceable by Ras85D05703

      (Rorth, 1996)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The rough eye phenotype caused when Gap1EP45 expression is driven by Scer\GAL4hs.2sev is strongly enhanced if the flies are also homozygous for Ras85D05703.

      (Rorth, 1996)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      EP45
      (Rorth, 1996)
      Gap1EP45
      (Walker et al., 2006)
      RasGAP1EP45
      Name Synonyms
      Secondary FlyBase IDs
        References (3)