FB2026_02 , released June 18, 2026
Allele: Dmel\Adh+tS
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General Information
Symbol
Dmel\Adh+tS
Species
D. melanogaster
Name
FlyBase ID
FBal0059531
Feature type
allele
Associated gene
Dmel\Adh
Associated Insertion(s)
Carried in Construct
P{Adh.FRT+Daff\Adh.loxP.SH}
P{Adh.FRT+loxP}
Key Links
Transgenic product class
wild_type
(Siegal and Hartl, 1996)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Siegal and Hartl, 1996)
Mutagen
in vitro construct
(Siegal and Hartl, 1996)
Progenitor genotype
AdhS
(Siegal and Hartl, 1996)
Carried in construct
P{Adh.FRT+Daff\Adh.loxP.SH}
P{Adh.FRT+loxP}
Cytology
Description

Fragment encompassing the Adh gene; encodes the AdhS variant.

(Siegal and Hartl, 1996)
Allele components
Component
Use(s)
Regulatory region(s)
Adh
Encoded product / tool
Adh
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying Adh+tS in an Adh- background show a high survival rate on medium supplemented with 0, 3, 6 or 9% ethanol, with an average survival rate of 89% on the medium containing 9% ethanol. These flies show a strong preference for oviposition on ethanol-containing medium, as do D.melanogaster flies carrying Daff\Adh+tAA1 in an Adh- background.

      (Siegal and Hartl, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P1\cre-mediated excision of w+mC and Daff\Adh+tAA1 leaves Adh+tS flanked by an Scer\FRT site on one side and a P1\loxP on the other. Exists in clones, not reported as being germ-line transmitted.

      (Siegal and Hartl, 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Adh+tS
      Name Synonyms
      Secondary FlyBase IDs
        References (3)