FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Abd-Br.hs
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General Information
Symbol
Dmel\Abd-Br.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0059537
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

cDNA encoding the r isoform is expressed under the control of an Hsp70 promoter.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Abd-Br.hs using heat shock during the late cellular blastoderm stage usually results in the failure of germ band retraction. Abdominal denticle belts are reduced in size, approaching the shape of thoracic denticle belts, although the denticle hairs remain abdominal in character. The first thoracic denticle belt is narrower than wild-type and the T1 beard is reduced or missing. The denticles of the second and third thoracic segments are wider and thicker than normal, appearing abdominal in character. In some cases complete denticle belts do not form ventrally, and patches of abdominal type denticle hairs are seen in ventro-lateral positions of the thoracic and abdominal segments. Ventral pits are often seen in abdominal segments. Rudimentary filzkorper and/or perispiracular hairs are occasionally seen in the most posterior abdominal segments, and rarely as far anteriorly as thoracic segments. Head involution is severely inhibited and denticle belts are often seen in the cephalic segments, sometimes forming belts. Tubular structures resembling fragments of the posterior tracheal system appear reiterated in anterior segments. Expression of Abd-Br.hs using heat shock during the first 24 hours of the third larval instar stage often results in transformation of distal antennal structures into distal leg structures. The arista is transformed into tarsal leg and tarsal claws occasionally develop in the distalmost regions of the transformed leg tissue. Part of the third antennal segment is sometimes transformed towards more proximal leg tissue, producing leg bristles. Many of these animals do not eclose from the pupal case. Expression of Abd-Br.hs using heat shock for 30 minutes during the second day of the third larval instar stage results in late larval or early pupal lethality in most cases.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Abd-Br.hs
Name Synonyms
Secondary FlyBase IDs
    References (1)