FB2026_03 , released September 17, 2026
Allele: LTSV\RBZhs.prd2
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General Information
Symbol
LTSV\RBZhs.prd2
Species
S. Lucerne transient streak virus
Name
FlyBase ID
FBal0060590
Feature type
allele
Associated gene
LTSV\RBZ
Associated Insertion(s)
Carried in Construct
P{prdRbz.2}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Vanario-Alonso et al., 1995)
Progenitor genotype
Carried in construct
P{prdRbz.2}
Cytology
Description

An Hsp70 promoter drives expression of a ribozyme that is designed to cleave prd mRNA at a GUC site between nucleotides +1167 and +1168, between the paired box and the homeobox. The ribozyme consists of a 24 base hammerhead catalytic centre flanked by 8-11 bases complementary to the prd mRNA target region.

(Vanario-Alonso et al., 1995)
Allele components
Component
Use(s)
Encoded product / tool
LTSV\RBZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heat induced expression at an early stage of development (about 2.5 hours) generated a pair-rule phenotype in about 15% of embryos and a mild prd-like phenotype in 25% of embryos. Heat induced expression after 4-5 hours of development (the time of prd expression in the head segments) causes grossly abnormal larval head structures. Ventral organ and maxillary chemosensory organs are missing and the dorsal cirri row is reduced.

      (Vanario-Alonso et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      LTSV\RBZhs.prd2
      RBZhs.prd2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)