FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cblhs.2sev
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General Information
Symbol
Dmel\Cblhs.2sev
Species
D. melanogaster
Name
FlyBase ID
FBal0060763
Feature type
allele
Associated gene
Dmel\Cbl
Associated Insertion(s)
Carried in Construct
P{sE[D-Cbl]}
Key Links
Transgenic product class
cDNA
(Meisner et al., 1997)
wild_type
(Meisner et al., 1997)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Meisner et al., 1997)
wild_type
(Meisner et al., 1997)
Mutagen
in vitro construct
(Meisner et al., 1997)
Progenitor genotype
Carried in construct
P{sE[D-Cbl]}
Cytology
Description

Expression of Cbl cDNA is driven by an Hsp70 promoter and two copies of sev enhancer.

(Meisner et al., 1997)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Cbl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In sev6; SosJC2 double heterozygotes an R7 cell develops in only 17% of the ommatidia, raising the level of Cbl essentially eliminates development of R7 cells. Expression in wild type flies does not alter the wild type phenotype.

      (Meisner et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Cblhs.2sev
      Name Synonyms
      Secondary FlyBase IDs
        References (1)