FlyBase Allele Report: Dmel\14-3-3ζ[E16]

General Information

Symbol

Dmel\14-3-3ζ^E16

Species

D. melanogaster

Name

FlyBase ID

FBal0060814

Feature type

allele

Associated gene

Dmel\14-3-3ζ

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Kockel et al., 1997, Mlodzik, 1997.5.10)

Progenitor genotype

14-3-3ζ⁰⁷¹⁰³

(Kockel et al., 1997, Mlodzik, 1997.5.10)

Cytology

Description

Imprecise excision of the P{PZ} element, deleting 1957bp, including exons I and I'.

(Kockel et al., 1997)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

2R:10,099,525..10,101,488 [+]

Comment:

mprecise excision of the P{PZ} element, deleting 1957bp, including exons I and I'.

(Kockel et al., 1997)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Isaksson et al., 1997, Kockel et al., 1997)

Phenotype Manifest In

Detailed Description

Statement

Reference

Homozygous clones are not recovered in a wild-type background or in flies carrying Ras85D^V12.sev, but are recovered in flies carrying phl::tor^12D.hs.sev.

(Kockel et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

14-3-3ζ^E16/14-3-3zeta[+] is a suppressor of visible phenotype of faf^BX4

(Isaksson et al., 1997)

Phenotype Manifest In

Suppressor of

Statement

Reference

14-3-3ζ^E16/14-3-3zeta[+] is a suppressor of photoreceptor cell R1 | ectopic phenotype of faf^BX4

(Isaksson et al., 1997)

14-3-3ζ^E16/14-3-3zeta[+] is a suppressor of photoreceptor cell R2 | ectopic phenotype of faf^BX4

(Isaksson et al., 1997)

14-3-3ζ^E16/14-3-3zeta[+] is a suppressor of photoreceptor cell R3 | ectopic phenotype of faf^BX4

(Isaksson et al., 1997)

14-3-3ζ^E16/14-3-3zeta[+] is a suppressor of photoreceptor cell R4 | ectopic phenotype of faf^BX4

(Isaksson et al., 1997)

14-3-3ζ^E16/14-3-3zeta[+] is a suppressor of photoreceptor cell R5 | ectopic phenotype of faf^BX4

(Isaksson et al., 1997)

14-3-3ζ^E16 is a suppressor of photoreceptor cell R6 | ectopic phenotype of faf^BX4

(Isaksson et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

The extra outer photoreceptor cell phenotype seen in faf^BX4 homozygotes is dominantly suppressed by 14-3-3ζ^E16, with the average number of outer photoreceptor cells per ommatidium being reduced to 6.4.

(Isaksson et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

14-3-3ζ^E16 is rescued by 14-3-3ζ^tKa

(Kockel et al., 1997)

Not rescued by

14-3-3ζ^E16 is not rescued by 14-3-3ζ^arm.PK

(Kockel et al., 1997)

Comments

The lethality is rescued by 14-3-3ζ^tKa but not by 14-3-3ζ^arm.PK.

(Kockel et al., 1997)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

Y12573

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

14-3-3^E16

14-3-3ζ^E16

E-16

(Kockel et al., 1997)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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