FB2026_02 , released June 18, 2026
Allele: Dmel\Abd-BFab7-12
Open Close
General Information
Symbol
Dmel\Abd-BFab7-12
Species
D. melanogaster
Name
FlyBase ID
FBal0062277
Feature type
allele
Associated gene
Dmel\Abd-B
Associated Insertion(s)
Carried in Construct
Also Known As
Fab-712
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Mihaly et al., 1997)
Progenitor genotype
Abd-Bblt
(Mihaly et al., 1997)
Cytology
Description

Imprecise excision of the P{bluetail} element, deleting sequences both proximal and distal to the site of the P{bluetail} insertion.

(Mihaly et al., 1997)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous males have no apparent tissue in A6.

      (Hogga and Karch, 2002)

      Flies show a dominant Fab-7 gain of function phenotype indistinguishable from the Abd-BFab7-1 phenotype. Homozygotes show complete transformation of abdominal segment A6 to A7.

      (Mihaly et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The AntpNs/+ antenna-to-leg transformation phenotype is exacerbated by Abd-BFab7-12 (which deletes the Fab-7 element) after a AntpNs Abd-BFab7-12 stock has been maintained for several generations; no difference in the AntpNs phenotype is seen immediately after the establishment of the AntpNs Abd-BFab7-12 stock, however, an exacerbation of the AntpNs phenotype emerges in subsequent generations of the stock, reaching a plateau after 3 to 5 generations.

      Abd-BFab7-12 (which deletes the Fab-7 element) induces a significant increase in the number of sex comb teeth in the T1 leg in ScrW Scr4/+ males (mutations in cis).

      (Bantignies et al., 2011)

      The heterozygous gain of function phenotype is unchanged in a Polycomb group mutant background or a trxE2/+ background.

      (Mihaly et al., 1997)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Abd-BFab7-12
      Fab-712
      (Bantignies et al., 2011, Hogga and Karch, 2002, Mihaly et al., 1997)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)