FB2026_02 , released June 18, 2026
Allele: Dmel\ninaEhs.PK
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General Information
Symbol
Dmel\ninaEhs.PK
Species
D. melanogaster
Name
heat shock construct a of Kumar
FlyBase ID
FBal0062529
Feature type
allele
Associated gene
Dmel\ninaE
Associated Insertion(s)
Carried in Construct
P{hs-ninaE}
Key Links
Transgenic product class
cDNA
(Kumar et al., 1997)
wild_type
(Kumar et al., 1997)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Kumar et al., 1997)
wild_type
(Kumar et al., 1997)
Mutagen
in vitro construct
(Kumar et al., 1997)
Progenitor genotype
Carried in construct
P{hs-ninaE}
Cytology
Description

Construct: Expression of a ninaE cDNA is placed under heat shock control.

(Kumar et al., 1997)
Allele components
Component
Use(s)
Encoded product / tool
ninaE
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Rhabdomere structure is lost in unshocked photoreceptors at 12 hours posteclosion: curtains of rhabdomere membrane invade photoreceptor cytoplasm, similar to ninaE17. ERG recordings demonstrate response amplitudes are reduced and off-transients are absent. Receptor cell R7 is unaffected. Substantial rhabdomere rescue is seen at 12 hours posteclosion in a fly heat shocked between 76 and 871% of pupal development. Response amplitudes and off-transients are comparable to wild type. Heat shock at a later stage of pupal development fails to rescue the rhabdomere phenotype, ERG is similar to ninaE17.

      (Kumar et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ninaEhs.PK
      Name Synonyms
      heat shock construct a of Kumar
      (Kumar et al., 1997)
      Secondary FlyBase IDs
        References (1)