FB2026_02 , released June 18, 2026
Allele: Ecol\lacZNUC.UAS
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General Information
Symbol
Ecol\lacZNUC.UAS
Species
E. coli
Name
FlyBase ID
FBal0063962
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{UAS-lacZ.NUC}
Also Known As
UAS-nuc-lacZ, P{UAS::N.lac-Z}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Miller et al., 2001, Miller et al., 2001, Jacobsen et al., 1998, Huppert et al., 1997)
Progenitor genotype
Carried in construct
P{UAS-lacZ.NUC}
Cytology
Description

UASt regulatory sequences drive expression of a lacZ reporter that is tagged with a nuclear localization signal (Tag:NLS(SV40-largeT)).

(Jacobsen et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
lacZ
Tagged with
Tag:NLS(SV40-largeT)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference

      ScerGAL4-targeted reporter: expression of EcollacZ reflects action of enhancer/promoter elements driving GAL4 in the same cell.Product localized to nucleus: the β-galactosidase protein produced carries a nuclear localization signal.

      (Huppert et al., 1997)

      ScerGAL4-targeted reporter; β-galactosidase distribution reflects action of enhancer/promoter elements driving GAL4 in the same cell.β-galactosidase product localized to nucleus.

      (Huppert et al., 1997)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      T.L. Jacobsen and M.A.T. Muskavitch

      (Huppert et al., 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Ecol\lacZN.Scer\UAS
      Ecol\lacZNUC.Scer\UAS
      Ecol\lacZNUC.UAS
      lacZNUC.UAS
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0124242
      References (14)