FlyBase Allele Report: Dmel\hep[rh1]

General Information

Symbol

Dmel\hep^rh1

Species

D. melanogaster

Name

FlyBase ID

FBal0065841

Feature type

allele

Associated gene

Dmel\hep

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Holland et al., 1997)

Phenotype Manifest In

Detailed Description

Statement

Reference

The lethality of hemizygous males is rescued by Mmus\Prkmk7^Ubi-p63E.PH in 42% of cases. Some of the males produced are fully fertile and viable, but the majority of adult males have defects in the dorsal thorax and in the development and rotation of the anal plate and genital arches. The lethality of hemizygous males is not significantly rescued by Mmmm\Sek1^Ubi-p63E.PH or Xlae\Mek2^Ubi-p63E.PH.

(Holland et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

hep^rh1 has lethal phenotype, non-suppressible by Mmmm\Sek1^Ubi-p63E.PH

(Holland et al., 1997)

hep^rh1 has lethal phenotype, non-suppressible by Xlae\map2k4.L^Ubi-p63E.PH