FlyBase Allele Report: Dmel\N[ANK.sev]

General Information

Symbol

Dmel\N^ANK.sev

Species

D. melanogaster

Name

FlyBase ID

FBal0083321

Feature type

allele

Associated gene

Dmel\N

Associated Insertion(s)

Carried in Construct

P{sev-N.ANK}

Key Links

Transgenic product class

inframe_deletion

(Matsuno et al., 1997)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Matsuno et al., 1997)

Mutagen

in vitro construct

(Matsuno et al., 1997)

Progenitor genotype

Carried in construct

P{sev-N.ANK}

Cytology

Description

Construct: N cDNA encoding amino acids 1890-2108 (ANK repeat region) is cloned downstream of the Act79B translation initiation codon and upstream of Adh 3' untranslated region. Fusion is expressed from the sev promoter.

(Matsuno et al., 1997)

Allele components

Component

Use(s)

Regulatory region(s)

sev

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | dominant

(Matsuno et al., 1997)

Phenotype Manifest In

cone cell

(Matsuno et al., 1997)

photoreceptor cell R7

(Matsuno et al., 1997)

Detailed Description

Statement

Reference

Rough eye phenotype. Eyes have ommatidial clusters lacking one or two cone cells and lacking R7. Phenotype is enhanced by expression of N^act.sev.

(Matsuno et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

N^ANK.sev has visible | dominant phenotype, enhanceable by Delta^5F

(Matsuno et al., 1997)

Phenotype Manifest In

Enhanced by

Statement

Reference

N^ANK.sev has cone cell phenotype, enhanceable by Delta^5F

(Matsuno et al., 1997)

N^ANK.sev has photoreceptor cell R7 phenotype, enhanceable by Delta^5F

(Matsuno et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

N^ANK.sev

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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