FB2025_01 , released February 20, 2025
Allele: Dmel\EcRA612V
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General Information
Symbol
Dmel\EcRA612V
Species
D. melanogaster
Name
FlyBase ID
FBal0083500
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

Amino acid replacement: A?V.

Mutation is in amino acid 612 of the EcR-B1 open reading frame, in the ligand-binding domain.

Nucleotide substitution: C?T.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Nucleotide change:

C6093390T

Reported nucleotide change:

C?T

Amino acid change:

A583V | EcR-PA; A612V | EcR-PB; A403V | EcR-PC; A583V | EcR-PD; A583V | EcR-PE; A612V | EcR-PG

Reported amino acid change:

A612V

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Some EcRA612V/EcRM554fs animals survive to the third larval instar stage, but they do not pupariate.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
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Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
EcRA612V
Name Synonyms
Secondary FlyBase IDs
    References (1)