FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pumunspecified
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General Information
Symbol
Dmel\pumunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0086364
Feature type
allele
Associated gene
Dmel\pum
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Gonads in mutant larvae at the larval/pupal transition contain developed cysts.

        (Gilboa and Lehmann, 2004)

        Many pumunspecified homozygous ovarioles completely lack germ cells. Those that do not have germaria containing few germ cells, linked to a few defective egg chambers.

        (Gilboa et al., 2003)

        Embryos derived from pumunspecified mutant females lack abdominal segments but have pole cells. Escapers have abnormal bristles.

        (Tearle and Nusslein-Volhard, 1987)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        pumunspecified is a suppressor of visible phenotype of nanosGMR.PW

        (Wharton et al., 1998)
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        pumunspecified is a suppressor of eye phenotype of nanosGMR.PW

        (Wharton et al., 1998)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Many zpgunspecified; pumunspecified ovarioles are empty. Ovarioles with germ-cells look more like those seen in zpgunspecified single mutants than in pumunspecified single mutants: few germ cells at the tip of the ovariole. However, the double mutants do make slightly more egg chambers that zpgunspecified single mutants.

        (Gilboa et al., 2003)

        Suppresses the rough eye phenotype of flies carrying nosGMR.PW.

        (Wharton et al., 1998)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        pumunspecified is rescued by pumnanos.PB

        (Barker et al., 1992)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        pumunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (7)