FB2026_02 , released June 18, 2026
Allele: Dmel\I-elementRTaseHN.hs
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General Information
Symbol
Dmel\I-element\RTaseHN.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0086819
Feature type
allele
Associated gene
I-element\RTase
Associated Insertion(s)
Carried in Construct
P{hs-I-element\RTase.HN}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Busseau et al., 1998)
Progenitor genotype
Carried in construct
P{hs-I-element\RTase.HN}
Cytology
Description

An Hsp70 promoter drives expression of I-element nucleotides 1489 to 5572 (coordinates according to FBrf0043891) which encode I-element\RTase and the 3' end of the I-element. An Hsp70 termination signal is fused downstream of the 3' end of the I-element sequences.

(Busseau et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
I-element\RTase
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Does not act as a repressor of I-element activity.

      (Malinsky et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P{IviP2} can be mobilised in the germ line of strongly reactive females in the absence of active I-elements, when it is transcomplemented by I-element\RTase protein encoded by P{hs-I-element\RTase.HN}.

      (Busseau et al., 1998)

      I-element\RTaseHN.hs can transcomplement the non-autonomous P{I-element.T:HA1.Δnuc} element, resulting in high frequencies of transposition of the P{I-element.T:HA1.Δnuc} element in the germ line of females containing I-element\RTaseHN.hs.

      (Robin et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      I-element\RTaseHN.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (3)