FlyBase Allele Report: Dmel\bol[unspecified]

General Information

Symbol

Dmel\bol^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0089441

Feature type

allele

Associated gene

Dmel\bol

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal meiotic cell cycle | male

(Xu et al., 2003)

Phenotype Manifest In

spermatid

(Xu et al., 2003)

spermatozoon

(Xu et al., 2003)

testis

(Xu et al., 2003)

Detailed Description

Statement

Reference

Germ cells are arrested before meiosis in mutant testes. The mutant testis contains only somatic cells, germ line stem cells and arrested and degenerating cysts of premeiotic spermatocytes. No mature spermatids are seen.

(Xu et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

bol^unspecified has abnormal meiotic cell cycle | male phenotype, suppressible by Hsap\BOLL^βTub85D.PX

(Xu et al., 2003)

NOT suppressed by

Statement

Reference

bol^unspecified has male sterile phenotype, non-suppressible by Hsap\BOLL^βTub85D.PX

(Xu et al., 2003)

Enhancer of

Statement

Reference

bol^unspecified, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Cln3^UAS.cTa, Scer\GAL4^GMR.PF

(Tuxworth et al., 2011)

bol^unspecified, Scer\GAL4^en-e16E is an enhancer of visible phenotype of Cln3^UAS.cTa, Scer\GAL4^en-e16E

(Tuxworth et al., 2011)

Phenotype Manifest In

Suppressed by

Statement

Reference

bol^unspecified has spermatid phenotype, suppressible by Hsap\BOLL^βTub85D.PX

(Xu et al., 2003)

Enhancer of

Statement

Reference

bol^unspecified, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Cln3^UAS.cTa, Scer\GAL4^GMR.PF

(Tuxworth et al., 2011)

bol^unspecified, Scer\GAL4^en-e16E is an enhancer of wing blade phenotype of Cln3^UAS.cTa, Scer\GAL4^en-e16E

(Tuxworth et al., 2011)

bol^unspecified, Scer\GAL4^en-e16E is an enhancer of wing margin phenotype of Cln3^UAS.cTa, Scer\GAL4^en-e16E

(Tuxworth et al., 2011)

bol^unspecified, Scer\GAL4^en-e16E is an enhancer of wing vein phenotype of Cln3^UAS.cTa, Scer\GAL4^en-e16E

(Tuxworth et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of bol^unspecified under the control of Scer\GAL4^GMR.PF enhances the cln3^Scer\UAS.cTa-overexpression phenotypes in the eye.

Co-expression of bol^unspecified under the control of Scer\GAL4^en-e16E enhances the cln3^Scer\UAS.cTa-overexpression phenotypes in the wing.

(Tuxworth et al., 2011)

Xenogenetic Interactions

Statement

Reference

The meiotic defects of bol^unspecified males are rescued by Hsap\BOLL^βTub85D.PX : many postmeiotic spermatid bundles are seen in the testis in these flies. However, fertility is not restored in these animals.

(Xu et al., 2003)

Complementation and Rescue Data

Partially rescued by

bol^unspecified is partially rescued by bol^βTub85D.PE

(Xu et al., 2003)

bol^unspecified is partially rescued by bol^βTub85D.PE

(Eberhart et al., 1996)

Comments

bol[unspecified]The meiotic defects of bol^unspecified males are rescued by bol^βTub85D.PE : many postmeiotic spermatid bundles are seen in the testis in these flies. However, fertility is not restored in these animals.

(Xu et al., 2003)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

bol^unspecified

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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