FlyBase Allele Report: Dmel\N[ECN.GV.3.hs]

General Information

Symbol

Dmel\N^ECN.GV.3.hs

Species

D. melanogaster

Name

FlyBase ID

FBal0090681

Feature type

allele

Associated gene

Dmel\N

Associated Insertion(s)

Carried in Construct

P{N^ECN-GV.3}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Struhl and Adachi, 1998)

Progenitor genotype

N^GV.3.hs

(Struhl and Adachi, 1998)

Carried in construct

P{N^ECN-GV.3}

Cytology

Description

Deletion of virtually all of the extracellular domain including all 36 EGF repeats and the LNR domain.

(Struhl and Adachi, 1998)

Allele components

Component

Use(s)

Regulatory region(s)

Hsp70

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

wild-type

(Struhl and Adachi, 2000, Struhl and Adachi, 1998)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

N^ECN.GV.3.hs is a non-suppressor of neurogenic phenotype | maternal effect | embryonic stage 8 phenotype of amx¹

(Michellod and Randsholt, 2008)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

The heat-shocked progeny from heterozygous amx¹ females crossed to N^{ECN.3.hs.T:Scer\GAL4,T:Hsim\VP16} males hatch at a similar rate to wild type and are viable.

The neurogenic phenotypes seen in stage 8 embryos when homozygous amx¹ mutant females are crossed to N^{ECN.3.hs.T:Scer\GAL4,T:Hsim\VP16} males (heat-shocked before the first delamination round) are similar to those seen when amx¹ females are crossed to wild type males.

(Michellod and Randsholt, 2008)

Alleviates the ventral epidermis phenotype of Df(3R)Dl-X43 mutant embryos.

(Struhl and Adachi, 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

N^ECN.GV.3.hs rescues N^XK11

(Struhl and Adachi, 2000)

N^ECN.GV.3.hs rescues N^XK11

(Struhl and Adachi, 1998)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

GAL4::N::VP16^ECN.3.hs

N^{ECN.3.hs.T:Scer\GAL4,T:Hsim\VP16}

N^ECN.GV.3.hs

N^ECN-GV#3

(Struhl and Adachi, 1998)

N^ECN-GV3

(Chan and Jan, 1998)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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