FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Polr2A120
Open Close
General Information
Symbol
Dmel\Polr2A120
Species
D. melanogaster
Name
FlyBase ID
FBal0091639
Feature type
allele
Associated gene
Dmel\Polr2A
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Nucleotide substitution: C4182T. Amino acid replacement: R789Q.

    (Krasnoselskaya et al., 1998)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    X:11,566,938..11,566,938 [-]
    Nucleotide change:

    G11566938A

    Reported nucleotide change:

    C4182T

    Amino acid change:

    R789Q | Polr2A-PA

    Reported amino acid change:

    R789Q

    (Krasnoselskaya et al., 1998)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressed by
        Statement
        Reference

        Polr2A120 has phenotype, suppressible by Polr2BS1

        (Krasnoselskaya et al., 1998)

        Polr2A120 has phenotype, suppressible by Polr2BS8

        (Krasnoselskaya et al., 1998)

        Polr2A120 has phenotype, suppressible by Polr2BSM

        (Krasnoselskaya et al., 1998)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Strongly suppressed by RpII140S1 or RpII140S8.

        (Krasnoselskaya et al., 1998)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        3A-b35
        Polr2A120
        RpII215120
        Name Synonyms
        Secondary FlyBase IDs
          References (1)