FlyBase Allele Report: Dmel\frtz[unspecified]

General Information

Symbol

Dmel\frtz^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0092992

Feature type

allele

Associated gene

Dmel\frtz

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity

(Collier et al., 2005)

abnormal planar polarity | adult stage

(Wang et al., 2017)

visible

(Collier et al., 2005)

visible | adult stage

(Wang et al., 2017)

Phenotype Manifest In

bract

(Collier et al., 2005)

leg

(Collier et al., 2005)

leg joint | ectopic

(Collier et al., 2005)

leg sensillum

(Collier et al., 2005)

tarsal segment 3

(Collier et al., 2005)

tarsal segment 4

(Collier et al., 2005)

wing hair

(Wang et al., 2017)

Detailed Description

Statement

Reference

frtz^unspecified homozygous adults display multiple hair cell and abnormal hair polarity phenotypes.

(Wang et al., 2017)

Legs of adult mutant flies show multiple cell hairs of abnormal polarity, multiple bracts and occasionally have partially formed ectopic joints in the third and fourth tarsal segments.

(Collier et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

frtz^unspecified has visible | adult stage phenotype, suppressible by frtz::pk^UAS.mCherry/Scer\GAL4^Act.PU

(Wang et al., 2017)

frtz^unspecified has abnormal planar polarity | adult stage phenotype, suppressible by frtz::pk^UAS.mCherry/Scer\GAL4^Act.PU

(Wang et al., 2017)

Phenotype Manifest In

Suppressed by

Statement

Reference

frtz^unspecified has wing hair phenotype, suppressible by frtz::pk^UAS.mCherry/Scer\GAL4^Act.PU

(Wang et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The multiple hair cell and abnormal hair polarity phenotypes observed in frtz^unspecified mutant flies are strongly suppressed by expression of frtz::pk^{Scer\UAS.T:Disc\RFP-mCherry} under the control of Scer\GAL4^Act.PU in the mutant background.

(Wang et al., 2017)

The gain-of-function tissue polarity phenotype in the wing caused by overexpression of pk^{sple.Scer\UAS} under the control of Scer\GAL4^Act is blocked if the flies are simultaneously mutant for frtz^unspecified, with the double mutant phenotype resembling that of frtz^unspecified single mutants. The tissue polarity phenotype seen in the wings of flies expressing stan^Scer\UAS.cUa under the control of Scer\GAL4^bi-md653 is blocked if the flies are simultaneously mutant for frtz^unspecified, with the double mutant phenotype resembling that of frtz^unspecified single mutants. The multiple wing hair phenotype of trc^unspecified clones in the wing is not suppressed by frtz^unspecified. No evidence of a domineering nonautonomy wing hair polarity phenotype is seen in fz²¹ clones in a frtz^unspecified background.

(Collier et al., 2005)

fry¹ frtz^unspecified double mutant clones in the wing have a much stronger phenotype than either single mutant.

(Cong et al., 2001)

Show no interaction with the dominant wing basal cell 1 swirl phenotype of Vang^Tbs42.

(Taylor et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

frtz^unspecified

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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