FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Trfs10
Open Close
General Information
Symbol
Dmel\Trfs10
Species
D. melanogaster
Name
FlyBase ID
FBal0093999
Feature type
allele
Associated gene
Dmel\Trf
Associated Insertion(s)
P{?lacW}Trfs10
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Crowley, 1998)
Progenitor genotype
Trf1
(Crowley, 1998)
Associated Insertion(s)
P{?lacW}Trfs10
Cytology
Description

Deletion of 3kb from the centre of the P{lacW} insertion, deleting all/part of the w gene.

(Crowley, 1998)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Severe spermatogenic defects: an alteration in the distribution of stages of spermatogenesis. Mutation slightly reduces the number of enlarged primary spermatocytes to approximately 10% the wild type level, resulting in a cluster of these cells close to the apical end of the testis.

      (Crowley, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The male sterile phenotype is probably due to alteration of the cis-acting transcription regulatory sequence at the Trf site and this effect becomes more severe when a portion of the transposon is removed.

      (Crowley, 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Trfs10
      Name Synonyms
      Secondary FlyBase IDs
        References (1)