FB2026_02 , released June 18, 2026
Allele: Ecol\lacZFMRFa.Tv
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General Information
Symbol
Ecol\lacZFMRFa.Tv
Species
E. coli
Name
FlyBase ID
FBal0094474
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{FMRFa-lacZ.Tv}
Also Known As
Tv-lacZ
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Benveniste et al., 1998)
Progenitor genotype
Ecol\lacZhs43
(Benveniste et al., 1998)
Carried in construct
P{FMRFa-lacZ.Tv}
Cytology
Description

A 446bp Tv neuron-specific FMRFa enhancer sequence (-922bp to -476bp relative to the transcription start site) is fused upstream of a heat shock promoter driving lacZ reporter expression.

(Benveniste et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
FMRFa_WF17
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 17
      apterous-expressing neuron of the lateral cluster of the thorax Ap4 | subset
      (Benveniste et al., 1998)
      larval stage
      apterous-expressing neuron of the lateral cluster of the thorax Ap4 | subset
      (Benveniste et al., 1998)
      Additional Information
      Statement
      Reference

      EcollacZFmrf.Tv expresses in approximately 97% of embryonic Tv neurons, and 93% of first instar larval Tv neurons.

      (Benveniste et al., 1998)
       
      Marker for
      Reflects expression of
      FMRFa
      (Benveniste et al., 1998)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZFMRFa.Tv
      Ecol\lacZFmrf.Tv
      lacZFmrf.Tv
      Name Synonyms
      Secondary FlyBase IDs
        References (5)