FlyBase Allele Report: Dmel\stg[GS3120]

General Information

Symbol

Dmel\stg^GS3120

Species

D. melanogaster

Name

FlyBase ID

FBal0095187

Feature type

allele

Associated gene

Dmel\stg

Associated Insertion(s)

P{GSV1}stg^GS3120

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Toba et al., 1999)

Progenitor genotype

Associated Insertion(s)

P{GSV1}stg^GS3120

Cytology

Description

Insertion oriented to drive expression in the sense direction starting upstream of the coding region.

(Gregory et al., 2007)

Insertion of a P{GS} element at -135bp (relative to the transcription start site).

(Toba et al., 1999)

Allele components

Component

Use(s)

Inserted element

P{GSV1}

misexpression element

Regulatory region(s)

UASt

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:29,255,460..29,255,460

(Gregory et al., 2007, Toba et al., 1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority die, with Scer\GAL4^29BD

(Toba et al., 1999)

partially lethal - majority die, with Scer\GAL4^c355

(Toba et al., 1999)

visible, with Scer\GAL4^29BD

(Toba et al., 1999)

visible, with Scer\GAL4^c355

(Toba et al., 1999)

wild-type, with Scer\GAL4^dpp.blk1

(Toba et al., 1999)

wild-type, with Scer\GAL4^hs.2sev

(Toba et al., 1999)

Phenotype Manifest In

macrochaeta, with Scer\GAL4^c355

(Toba et al., 1999)

wing, with Scer\GAL4^29BD

(Toba et al., 1999)

Detailed Description

Statement

Reference

Flies expressing P{GS}stg^GS3120 under the control of Scer\GAL4^29BD show semi-lethality and have deformed wings. Flies expressing P{GS}stg^GS3120 under the control of Scer\GAL4^c355 show semi-lethality and have extra bristles.

(Toba et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

stg^GS3120/Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, pbl^UAS.cPa

(Gregory et al., 2007)

Suppressor of

Statement

Reference

stg^GS3120/Scer\GAL4^GMR.PF is a suppressor | partially of visible phenotype of Scer\GAL4^GMR.PF, pbl^{ΔDH497-549.UAS}

(Gregory et al., 2007)

Other

Statement

Reference

Scer\GAL4^en-e16E, pbl^RNAi.UAS, stg^GS3120 has abnormal mitotic cell cycle | third instar larval stage phenotype

(Gregory et al., 2007)

Phenotype Manifest In

Enhancer of

Statement

Reference

stg^GS3120/Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, pbl^UAS.cPa

(Gregory et al., 2007)

Suppressor of

Statement

Reference

stg^GS3120/Scer\GAL4^GMR.PF is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PF, pbl^{ΔDH497-549.UAS}

(Gregory et al., 2007)

stg^GS3120/Scer\GAL4^en-e16E is a suppressor | partially of wing | posterior phenotype of Scer\GAL4^en-e16E, pbl^RNAi.UAS

(Gregory et al., 2007)

stg^GS3120/Scer\GAL4^en-e16E is a suppressor | partially of wing | posterior & wing hair phenotype of Scer\GAL4^en-e16E, pbl^RNAi.UAS

(Gregory et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of stg^GS3120 does not significantly affect the hyperploid cell effects seen in Scer\GAL4^en-e16E, pbl^{dsRNA.Scer\UAS} wing discs, though it does strongly push cells from the G2 to the G1 fraction.

(Gregory et al., 2007)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

200493

y¹ w^67c23; P{GSV1}stg^GS3120/TM3, Sb¹ Ser¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

stg^GS3120

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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