FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Su(dpp)39CDE1
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General Information
Symbol
Dmel\Su(dpp)39CDE1
Species
D. melanogaster
Name
FlyBase ID
FBal0095569
Feature type
allele
Associated gene
Su(dpp)39CDE
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutants show no morphological defects.

        (Murthy and Gelbart, 1999)

        Su(dpp)39CDE1 is a dominant maternal effect suppressor of the dpp haploinsufficiency phenotype, but it turns out that homozygotes are perfectly viable and fertile on their own. Homozygous Su(dpp)39CDE1 mothers will enhance 3X and 4X dpp+ copy number; flies bearing 3 or 4 wild-type copies of dpp will die with greater frequency compared to their 2X siblings. Su(dpp)39CDE1/Deficiency also gives the same enhancement result, even though Deficiency/+ neither suppresses haploinsufficiency nor enhances >2X dpp+.

        (Murthy, 1999.3.3)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        Su(dpp)39CDE[+]/Su(dpp)39CDE1 is a suppressor of phenotype of dppH46

        (Murthy and Gelbart, 1999)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Su(dpp)39CDE homozygous mothers (but not heterozygotes) cause lethality of animals bearing more than two copies of dpp+.

        (Murthy and Gelbart, 1999)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Su(dpp)39CDE1
        Name Synonyms
        Secondary FlyBase IDs
          References (2)