FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Mmus\Hoxa2αTub84B.PP
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General Information
Symbol
Mmus\Hoxa2αTub84B.PP
Species
M. musculus
Name
α-Tubulin at 84B promoter construct of Percival-Smith
FlyBase ID
FBal0097220
Feature type
allele
Associated gene
Mmus\Hoxa2
Associated Insertion(s)
Carried in Construct
P{Mmus\Hoxa2.αTub84B.P}
Transgenic product class
wild_type
(Percival-Smith and Bondy, 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Percival-Smith and Bondy, 1999)
Mutagen
FLPase
(Percival-Smith and Bondy, 1999)
Progenitor genotype
Mmus\Hoxa2FRT.αTub84B
(Percival-Smith and Bondy, 1999)
Carried in construct
P{Mmus\Hoxa2.αTub84B.P}
Cytology
Description

The FRT cassette has been excised, juxtaposing the αTub84B promoter and Mmus\Hoxa2 coding sequences.

(Percival-Smith and Bondy, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
αTub84B
Encoded product / tool
Mmus\Hoxa2
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adults in which all cells express Mmus\Hoxa2αTub84B.PP are viable.

      (Percival-Smith and Bondy, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      pb27/pb20 flies have reduced maxillary palps and a proboscis to tarsus transformation. The reduced maxillary palp phenotype is not rescued by expression of Mmus\Hoxa2αTub84B.PP and the proboscis to tarsus transformation is replaced with a partial transformation of proboscis to arista in these flies.

      (Percival-Smith and Bondy, 1999)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mmus\Hoxa2αTub84B.PP
      Name Synonyms
      α-Tubulin at 84B promoter construct of Percival-Smith
      (Percival-Smith and Bondy, 1999)
      Secondary FlyBase IDs
        References (1)