FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ocUAS.cWa
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General Information
Symbol
Dmel\ocUAS.cWa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Wimmer
FlyBase ID
FBal0104467
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive oc expression.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos expressing ocScer\UAS.cWa under the control of Scer\GAL4nos.bcd3'UTR.T:Scer\GCN4 (where Scer\GAL4nos.bcd3'UTR.T:Scer\GCN4 is provided maternally) show 60% embryonic lethality. Only a few embryos survive the larval stages and become adults. 48% of the embryos show a weak distortion of the pharyngeal wall and defects in the mouth hooks, mostly lacking the internal part. Most of the remaining embryos (51%) show head involution defects. The number of stomatogastric nervous system precursor invaginations is drastically reduced in most embryos. Most surviving larvae derived from embryos expressing ocScer\UAS.cWa under the control of Scer\GAL4nos.bcd3'UTR.T:Scer\GCN4 (where Scer\GAL4nos.bcd3'UTR.T:Scer\GCN4 is provided maternally) have feeding problems, since food never reaches the midgut. In most larvae, the food is engorged at the caudal end of proventriculus and the gastric caeca.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
ocScer\UAS.cWa
ocUAS.cWa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Wimmer
Secondary FlyBase IDs
    References (1)