Embryos expressing ocScer\UAS.cWa under the control of Scer\GAL4nos.bcd3'UTR.T:Scer\GCN4 (where Scer\GAL4nos.bcd3'UTR.T:Scer\GCN4 is provided maternally) show 60% embryonic lethality. Only a few embryos survive the larval stages and become adults. 48% of the embryos show a weak distortion of the pharyngeal wall and defects in the mouth hooks, mostly lacking the internal part. Most of the remaining embryos (51%) show head involution defects. The number of stomatogastric nervous system precursor invaginations is drastically reduced in most embryos. Most surviving larvae derived from embryos expressing ocScer\UAS.cWa under the control of Scer\GAL4nos.bcd3'UTR.T:Scer\GCN4 (where Scer\GAL4nos.bcd3'UTR.T:Scer\GCN4 is provided maternally) have feeding problems, since food never reaches the midgut. In most larvae, the food is engorged at the caudal end of proventriculus and the gastric caeca.
E. Wimmer