FB2026_02 , released June 18, 2026
Allele: Zzzz\CAG20Q.UAS.Tag:HA
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General Information
Symbol
Zzzz\CAG20Q.UAS.Tag:HA
Species
a. artificial
Name
FlyBase ID
FBal0104695
Feature type
allele
Associated gene
Zzzz\CAG
Associated Insertion(s)
Carried in Construct
P{UAS-Zzzz\CAG.20Q}
Also Known As
UAS-20Q, UAS-Q20
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kazemi-Esfarjani and Benzer, 2000)
Progenitor genotype
Carried in construct
P{UAS-Zzzz\CAG.20Q}
Cytology
Description

UAS regulatory sequences drive expression of a 20 amino acid polyglutamine tract (derived from the pros gene) tagged with Tag:HA. The polyglutamine tract is flanked by 8 amino acids (MGGPPSTP) on the N-terminal side and 13 amino acids on the C-terminal side (TSRTYPYDVPDYA).

(Kazemi-Esfarjani and Benzer, 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Zzzz\CAG
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Zzzz\CAG20Q.Scer\UAS.T:Ivir\HA1 in the developing eye under the control of Scer\GAL4GMR.PF does not result in any significant structural defects in the eye.

      (Park et al., 2011)

      Scer\GAL4elav-C155-driven expression of Zzzz\CAG20Q.Scer\UAS.T:Ivir\HA1 does not have any adverse effect on survival or longevity of flies.

      (Mallik and Lakhotia, 2009)

      Expression of Zzzz\CAG20Q.Scer\UAS.T:Ivir\HA1, under the control of Scer\GAL4GMR.PF, does not result in any eye phenotype. The ommatidia and axonal projections in Zzzz\CAG20Q.Scer\UAS.T:Ivir\HA1, Scer\GAL4GMR.PF mutants are organised as in wild-type.

      (Sengupta and Lakhotia, 2006)

      Expression of Zzzz\CAG20Q.Scer\UAS.T:Ivir\HA1 in the developing eye under the control of Scer\GAL4GMR.PF does not generate a phenotypic, morphological change.

      Expression of Zzzz\CAG20Q.Scer\UAS.T:Ivir\HA1 in the developing nervous system under the control of Scer\GAL4Appl.G1a does not generate a phenotypic, morphological change.

      (Kazemi-Esfarjani and Benzer, 2002)

      Animals expressing Zzzz\CAG20Q.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PF eclose as adults with eyes that are morphologically normal and have normal pigment distribution.

      (Kazemi-Esfarjani and Benzer, 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Zzzz\CAG20Q.Scer\UAS.T:Ivir\HA1 and Mmus\PrnpP101L.Scer\UAS.T:Hsap\PRNP-3F4 in the developing eye under the control of Scer\GAL4GMR.PF does not result in any significant structural defects in the eye.

      (Park et al., 2011)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Zzzz\CAG20Q.Scer\UAS.T:Ivir\HA1
      Zzzz\CAG20Q.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (16)