FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\OptixUAS.cSa
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General Information
Symbol
Dmel\OptixUAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Seimiya
FlyBase ID
FBal0105135
Feature type
allele
Associated gene
Dmel\Optix
Associated Insertion(s)
Carried in Construct
P{UAS-Optix.S}
Also Known As
UAS-optix
Key Links
Transgenic product class
cDNA
(Seimiya and Gehring, 2000)
wild_type
(Seimiya and Gehring, 2000)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Seimiya and Gehring, 2000)
wild_type
(Seimiya and Gehring, 2000)
Mutagen
in vitro construct
(Seimiya and Gehring, 2000)
Progenitor genotype
Carried in construct
P{UAS-Optix.S}
Cytology
Description

UASt regulatory sequences drive expression of a full length Optix cDNA.

(Seimiya and Gehring, 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Optix
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of OptixScer\UAS.cSa under the control of Scer\GAL4dpp.blk1 results in the formation of ectopic eye structures in the antenna and the anterior medial region of the head, but not in the legs or wings. The normal eyes are reduced in size and rarely extra ocelli and interocellar bristles are detected around the vertex region. The frequency of induction of ectopic eyes is 20%.

      (Seimiya and Gehring, 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT suppressed by
      Statement
      Reference

      OptixUAS.cSa, Scer\GAL4dpp.blk1 has visible phenotype, non-suppressible by ey2

      (Seimiya and Gehring, 2000)
      Other
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      OptixUAS.cSa, Scer\GAL4dpp.blk1 has ocellus | ectopic phenotype, enhanceable by ey2

      (Seimiya and Gehring, 2000)
      NOT suppressed by
      Statement
      Reference

      OptixUAS.cSa, Scer\GAL4dpp.blk1 has eye | ectopic phenotype, non-suppressible by ey2

      (Seimiya and Gehring, 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Ectopic eyes are still produced if OptixScer\UAS.cSa is expressed under the control of Scer\GAL4dpp.blk1 in an ey2 background. The frequency of occurrence of ectopic eyes is not changed from when OptixScer\UAS.cSa is expressed under the control of Scer\GAL4dpp.blk1 in a wild-type background, but the frequency of induction of extra ocelli is increased.

      (Seimiya and Gehring, 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      OptixScer\UAS.cSa
      OptixUAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Seimiya
      (Seimiya and Gehring, 2000)
      Secondary FlyBase IDs
        References (4)