FB2026_03 , released September 17, 2026
Allele: Ecol\lacZrpr.4xRE
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General Information
Symbol
Ecol\lacZrpr.4xRE
Species
E. coli
Name
FlyBase ID
FBal0105173
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{rpr-lacZ.H.4xRE}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Brodsky et al., 2000)
Progenitor genotype
Carried in construct
P{rpr-lacZ.H.4xRE}
Cytology
Description

Expression of a lacZ reporter is governed by an Hsp70 minimal promoter and 4 copies of the p53 Response Element defined by analysis of the rpr upstream region.

(Brodsky et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
rpr_p53RE
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference

      Four copies of the p53 Response Element and a minimal Hsp70 promoter results in negligible EcollacZ expression in untreated embryos, but drives significant EcollacZ expression in radiation treated embryos.

      (Brodsky et al., 2000)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ecol\lacZrpr.4xRE
      Name Synonyms
      Secondary FlyBase IDs
        References (2)