FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\trioBX1B
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General Information
Symbol
Dmel\trioBX1B
Species
D. melanogaster
Name
FlyBase ID
FBal0117300
Feature type
allele
Associated gene
Dmel\trio
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Bateman et al., 2000)
Progenitor genotype
trioS137203
(Bateman et al., 2000)
Cytology
Description

Imprecise excision of P{lacW} of parental trioS137203.

(Bateman et al., 2000)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants show a short stop phenotype, with defects in the ability of nerve branches to reach target muscles. ISNb (where the effect is most pronounced) and SNa are most sensitive to the loss of trio activity. In addition, there are occasional defects in epidermal muscle attachment sites. The CNS also shows pathfinding errors resulting in breaks in the longitudinal connectives. The axons often fail to traverse the segment boundary.

      (Bateman et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      trioS137203/trioBX1B is partially rescued by Scer\GAL4elav-C155/trioUAS.cBa

      (Bateman et al., 2000)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      trioBX1B
      Name Synonyms
      Secondary FlyBase IDs
        References (1)