FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ovr1
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General Information
Symbol
Dmel\ovr1
Species
D. melanogaster
Name
FlyBase ID
FBal0117419
Feature type
allele
Associated gene
ovr
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Dellinger et al., 2000)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      At 36 or 38oC, ovr1/Df(1)HF396 hemizygotes typically stand motionless, and only infrequently walk a short distance (typically 2-3 body lengths), in contrast to wild-type flies which typically exhibit fast, uninterrupted walking and a generally high level of activity under these conditions. 50% of ovr1 flies show paralysis after 22.04 +/- 0.85 minutes at 38oC.

      (Dellinger et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      ovr1 is an enhancer of paralytic | recessive | heat sensitive phenotype of comt4

      (Dellinger et al., 2000)

      ovr1 is an enhancer of paralytic | recessive | heat sensitive phenotype of comt1

      (Dellinger et al., 2000)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      ovr1 accelerates the paralysis observed in comt1 and comt4 animals at 36oC (the time for 50% paralysis is reduced).

      (Dellinger et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a modifier of the comt1 paralytic phenotype.

      (Dellinger et al., 2000)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ovr
      (Dellinger et al., 2000)
      ovr1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)