FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hexe77
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General Information
Symbol
Dmel\hexe77
Species
D. melanogaster
Name
FlyBase ID
FBal0117496
Feature type
allele
Associated gene
hexe
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Riede, 2000, Riede, 1997)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethal and tumour inducing over the MBT chromosome. Homozygotes show the formation of melanotic tumours. Gaps in somatic pairing are seen in the polytene chromosomes of heterozygous salivary glands. Heterozygotes show resistance to 5mM hydroxyurea and to 1mM methyl methanesulfonate.

      (Riede, 2000)

      Shows strong somatic pairing defect in the salivary chromosomes. Causes significant melanotic tumor formation in larvae. Lethal when heterozygous with the MBT chromosome. Shows hyperplasia when heterozygous with the MBT chromosome.

      (Riede, 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      hexe77
      (Riede, 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)