FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Mmus\Map3k7ΔN.GMR
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General Information
Symbol
Mmus\Map3k7ΔN.GMR
Species
M. musculus
Name
FlyBase ID
FBal0117706
Feature type
allele
Associated gene
Mmus\Map3k7
Associated Insertion(s)
Carried in Construct
P{GMR-mTAK1.ΔN}
Transgenic product class
inframe_deletion
(Takatsu et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Takatsu et al., 2000)
Mutagen
in vitro construct
(Takatsu et al., 2000)
Progenitor genotype
Carried in construct
P{GMR-mTAK1.ΔN}
Cytology
Description

A truncated Mmus\Map3k7 cDNA, lacking the N terminal 22 amino acids, is expressed under the control of GMR regulatory sequences.

(Takatsu et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
GMR
Encoded product / tool
Mmus\Map3k7
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      All mutant flies show a severe eye phenotype. In the weakest lines eye size is less than 30% of the wild-type and ommatidial units are rarely identified. In addition photoreceptor cells and pigment granules are difficult to recognize. In the mutant pupal eye disc, cone cells, primary pigment cells and accessory cells exist in a disorganised array.

      (Takatsu et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Mmus\Map3k7ΔN.GMR has eye phenotype, suppressible by BacA\p35GMR.PH

      (Takatsu et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Proper numbers of cone cells and primary pigment cells are seen in Mmus\Tak1ΔN.GMR, BacA\p35GMR.PH pupal eye discs.

      (Takatsu et al., 2000)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mmus\Map3k7ΔN.GMR
      Mmus\Tak1ΔN.GMR
      Name Synonyms
      Secondary FlyBase IDs
        References (1)