FB2026_02 , released June 18, 2026
Allele: Dmel\gclunspecified
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General Information
Symbol
Dmel\gclunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0118218
Feature type
allele
Associated gene
Dmel\gcl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        In stage 14 embryos, about 1.2 pole cells are seen per embryo, compared to about 19.4 in wild-type.

        (Leatherman et al., 2000)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressed by
        Statement
        Reference

        gclunspecified has sterile phenotype, suppressible by Mmus\Gmcl1Hsp83.PL

        (Leatherman et al., 2000)
        Phenotype Manifest In
        Suppressed by
        Statement
        Reference

        gclunspecified has primordial germ cell phenotype, suppressible by Mmus\Gmcl1Hsp83.PL

        (Leatherman et al., 2000)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference

        The addition of Mmus\GclHsp83.PL to gclunspecified embryos suppresses the pole cell phenotype. Embryos have between 4.7 and 8.9 pole cells per embryo. Fertility of mutant adults is also increased.

        (Leatherman et al., 2000)
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        gclunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (4)