FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\enaunspecified
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General Information
Symbol
Dmel\enaunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0118246
Feature type
allele
Associated gene
Dmel\ena
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        The number of branches is significantly decreased in enaunspecified mutant class IV neuron dendritic trees. The number of short, high order branches is significantly reduced, while the branch length distribution is largely unaffected.

        (Dimitrova et al., 2008)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        ena[+]/enaunspecified is a suppressor of lethal | recessive | rescuable maternal effect | embryonic stage phenotype of Abl4

        (Grevengoed et al., 2001)
        Phenotype Manifest In
        NOT Suppressor of
        Statement
        Reference

        enaunspecified is a non-suppressor of phenotype of arm3

        (Cox et al., 2000)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Ectopic actin filaments do not form in enaunspecified capt10 double mutant follicle cell clones and F-actin levels are often decreased.

        (Baum and Perrimon, 2001)

        The embryonic lethality seen in Abl4 animals lacking both maternal and zygotic Abl function is significantly rescued if the female parents are also heterozygous for enaunspecified.

        (Grevengoed et al., 2001)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        enaunspecified
        enbunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (7)