FB2026_02 , released June 18, 2026
Allele: Dmel\emb3
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General Information
Symbol
Dmel\emb3
Species
D. melanogaster
Name
FlyBase ID
FBal0118250
Feature type
allele
Associated gene
Dmel\emb
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Roth et al., 2003)
Mutagen
ethyl methanesulfonate
(Collier et al., 2000)
Progenitor genotype
Cytology
Description

Amino acid replacement: ?488term.

(Roth et al., 2003)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:8,405,753..8,405,753 [+]
Nucleotide change:

T8405753A

Amino acid change:

L489term | emb-PA; L489term | emb-PB

Reported amino acid change:

?488term

Comment:

Reported as a TAG stop codon at position 488. Curator's note: the mutation was mapped to codon 489, which requires a single base change to get the

TAG stop codon.

(Roth et al., 2003)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      emb3 embryos show an decreased reoxygenation response after hypoxia compared to wild type.

      (Irisarri et al., 2009)

      The most advanced stage seen in emb3/Df(2L)N22-14 animals is the 2nd larval instar.

      (Collier et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      emb3
      (Irisarri et al., 2009, Roth et al., 2003)
      l(2)fy4-3
      (Collier et al., 2000)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)