FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\cg3
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General Information
Symbol
Dmel\cg3
Species
D. melanogaster
Name
FlyBase ID
FBal0119302
Feature type
allele
Associated gene
Dmel\cg
Associated Insertion(s)
?{}cg3
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Svendsen et al., 2000)
Progenitor genotype
Associated Insertion(s)
?{}cg3
Cytology
Description

Insertion of approximately 4.3kb in cg.

(Svendsen et al., 2000)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Most homozygotes survive until the pharate adult stage. Approximately 50% of cg1/cg3 animals eclose to adult stages, with most of the remaining animals dying as pharate adults. cg1/cg3 flies have defects in some combination of the posterior compartment longitudinal veins L4 and L5. Defects in vein L4, ranging from a slight thinning of the vein to gaps of increasing size are seen in 100% of wings. Defects in wing vein L5 are seen in less than 25% of flies. Rarely (less than 1%), outgrowths are seen in the costal region of the anterior wing margin. cg3/cg07659 animals survive to the pharate adult stage but never eclose. cg3/cg07659 males have highly disorganised sex combs with as much as a threefold increase in the number of sex comb teeth. The pre-apical bristle may also be duplicated. cg3/cg07659 legs discs show a substantial increase in the relative size of the anterior compartment.

      (Svendsen et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      cg[+]/cg3 is an enhancer of visible | dominant phenotype of ciW

      (Svendsen et al., 2000)
      Other
      Statement
      Reference

      Df(2R)en-11/+, cg3 has visible | dominant phenotype

      (Svendsen et al., 2000)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      cg[+]/cg3 is an enhancer of wing vein L4 phenotype of ciW

      (Svendsen et al., 2000)
      Other
      Statement
      Reference

      Df(2R)en-11/+, cg3 has wing vein L4 phenotype

      (Svendsen et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Df(2R)en-11/+ ; cg3/+ double heterozygotes have a gap in wing vein L4. The wing vein L4 defects observed in ciW/+ heterozygotes are enhanced by one copy of cg3.

      (Svendsen et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Arose as: a second site mutation generated in a P-excision screen on a P{PZ}H-15, b- cn- chromosome.

      (Svendsen et al., 2000)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      cg3
      Name Synonyms
      Secondary FlyBase IDs
        References (1)