FB2026_03 , released September 17, 2026
Allele: Dmel\Hmgcrclb3
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General Information
Symbol
Dmel\Hmgcrclb3
Species
D. melanogaster
Name
FlyBase ID
FBal0122100
Feature type
allele
Associated gene
Dmel\Hmgcr
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: A314T. Nucleotide substitution: G1508A. Amino acid replacement: G613S. Nucleotide substitution: G2405A. Nucleotide substitution: C3295A (silent substitution). Co-ordinates refer to the pNB36C cDNA.

    (Van Doren and Lehmann, 2001.2.14)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3R:23,748,544..23,748,544 [+]
    Nucleotide change:

    G23748544A

    Reported nucleotide change:

    G1508A

    Amino acid change:

    A314T | Hmgcr-PA

    Reported amino acid change:

    A314T

    Comment:

    one of three nucleotide substitutions reported in mutant strain (one silent).

    (Van Doren and Lehmann, 2001.2.14, Goodman and Chang, 1985)
    point_mutation
    3R:23,749,505..23,749,505 [+]
    Nucleotide change:

    G23749505A

    Reported nucleotide change:

    G2405A

    Amino acid change:

    G613S | Hmgcr-PA

    Reported amino acid change:

    G613S

    Comment:

    one of three nucleotide substitutions reported in mutant strain (one silent).

    (Van Doren and Lehmann, 2001.2.14, Goodman and Chang, 1985)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Strong allele.

        (Van Doren and Lehmann, 2001.2.14)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        29.29
        (Van Doren and Lehmann, 2001.2.14)
        Hmgcrclb3
        Name Synonyms
        Secondary FlyBase IDs
          References (1)