FB2026_02 , released June 18, 2026
Allele: Tcas\ftzhs.PL
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General Information
Symbol
Tcas\ftzhs.PL
Species
T. castaneum
Name
heat shock construct of Lohr
FlyBase ID
FBal0127260
Feature type
allele
Associated gene
Tcas\ftz
Associated Insertion(s)
Carried in Construct
P{hs-Tcas\ftz.L}
Transgenic product class
wild_type
(Lohr et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Lohr et al., 2001)
Mutagen
in vitro construct
(Lohr et al., 2001)
Progenitor genotype
Carried in construct
P{hs-Tcas\ftz.L}
Cytology
Description

Construct: A heat shock promoter drives expression of Tcas\ftz.

(Lohr et al., 2001)
Allele components
Component
Use(s)
Encoded product / tool
Tcas\ftz
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Tcas\ftzhs.PL using heat shock during larval development causes transformations of the antenna towards leg, with the arista taking on the characteristics of the tarsus. Expression of Tcas\ftzhs.PL using heat shock at 5.5 hours after egg laying results in head involution defects and transformation of T1 towards T2 (shown by a reduction in the ventral beard). Expression of Tcas\ftzhs.PL at the blastoderm stage results in an "anti-ftz" phenotype in 30-40% of embryos; most of the ftz-independent parasegments are deleted.

      (Lohr et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Tcas\ftzhs.PL
      Name Synonyms
      heat shock construct of Lohr
      (Lohr et al., 2001)
      Secondary FlyBase IDs
        References (1)