FlyBase Allele Report: Dmel\rhi[2-sL15]

General Information

Symbol

Dmel\rhi^2-sL15

Species

D. melanogaster

Name

FlyBase ID

FBal0129112

Feature type

allele

Associated gene

Dmel\rhi

Associated Insertion(s)

P{?PZ}rhi^2-sL15

Carried in Construct

Key Links

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Volpe et al., 2001)

Progenitor genotype

rhi⁰²⁰⁸⁶

(Volpe et al., 2001)

Associated Insertion(s)

P{?PZ}rhi^2-sL15

Cytology

Description

Internal deletion in the P{PZ} element, with no apparent loss of flanking DNA approximately 12kb 5' and 8.5kb 3' to the insertion site.

(Volpe et al., 2001)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

dorsal appendage

(Volpe et al., 2001)

egg chamber (with rhi^2-L12)

(Volpe et al., 2001)

nurse cell (with rhi^2-L12)

(Volpe et al., 2001)

nurse cell & chromatin (with rhi^2-L12)

(Volpe et al., 2001)

Detailed Description

Statement

Reference

16% of eggs laid by homozygous females are wild type, others have dorsal appendage defects. A "dumpless" phenotype, in which the nurse cells fail to transfer their contents to the oocyte is seen in 25% of cases. rhi^2-sL15/rhi^2-L12 egg chambers have normal nurse cell chromatin morphology up to stage S5, but only 20% have normal nurse cell chromatin morphology at other stages. 58% of the egg chambers have a persistant five-lobed chromatin phenotype. 6% of egg chambers are degenerating and 7% have an abnormal number of nurse cells.

(Volpe et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Induced with: l(2)2-L^sL15. Complementation testing, Southern blot analysis, transcript mapping and expression data suggestion that the lethality of this chromosome is not due to disruption of the rhi gene (and is due instead to l(2)2-L^sL15).

(Volpe et al., 2001)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

rhi^2-SL15

(Volpe et al., 2001)

rhi^2-sL15

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close